一、科研论文（近年代表性5篇）：
1.Yang ZT, Yeo SY, Yin YX, Lin ZH, Lee HM, Xuan YH*（通讯作者）, Cui Y, Kim SH. Tenascin-C, a Prognostic Determinant of Esophageal Squamous Cell Carcinoma. PLoS One. 2016,11(1).
2.Yang Z, Cui Y, Ni W, Kim S, Xuan Y*（通讯作者）. Gli1, a potential regulator of esophageal cancer stem cell, is identified as an independent adverse prognostic factor in esophageal squamous cell carcinoma. J Cancer Res Clin Oncol. 2017,143(2):243-254.
3.Zhao-Ting Yang, Wei-Dong Ni, Xin-Xin Liu, Yan-Hua Xuan*（通讯作者）, Yu-Jin. Tenascin-C is a diagnostic marker for cervical cancer and a potential marker for cancer-associated fibroblasts in cervical carcinoma. Int J Clin Exp Pathol. 2017,10(1):139-147.
4.Yang Z, Ni W, Cui C, Fang L, Xuan Y*（通讯作者）. Tenascin C is a prognostic determinant and potential cancer-associated fibroblasts marker for breast ductal carcinoma. Exp Mol Pathol. 2017,102(2):262-267.
5.Wei-Dong Ni, Zhao-Ting Yang, Chun-Ai Cui, Yan Cui, Long-Yun Fang, Yan-Hua Xuan*（通讯作者）. Tenascin-C is a potential cancer-associated fibroblasts marker and predicts poor prognosis in prostate cancer. Biochem Biophys Res Commun. 2017, 486(3):607-612.
6.Yan Cui, Chun-ai Cui, Zhao-ting Yang, Wei-dong Ni, Yu Jin, Yan-hua Xuan*（通讯作者）. Gli1 expression in cancer stem- like cells predicts poor prognosis in patients with lung squamous cell carcinoma. Exp Mol Pathol. 2017,102(2):347-353.
7.So-Young Yeo, Sang-Yun Ha, Keun-Woo Lee, Yan Cui, Zhao-Ting Yang, Yan-Hua Xuan*（通讯作者）, Seok-Hyung Kim. Twist1 is highly expressed in cancer-associated fibroblasts of esophageal squamous cell carcinoma with a prognostic significance. Oncotarget. 2017,8(39):65265-65280.
8.Ni W, Yang Z, Qi W, Cui C, Cui Y, Xuan Y*（通讯作者）. Gli1 is a potential cancer stem cell marker and predicts poor prognosis in ductal breast carcinoma. Hum Pathol. 2017,69;38-45.
9.Lan Liu, Zhaoting Yang, Weidong Ni, Yanhua Xuan*（通讯作者）. ADAMTS-6 is a predictor of poor prognosis in patients with esophageal squamous cell carcinoma. Exp Mol Pathol. 2018; 104 (2):134-139.
10.Piao L, Yang Z, Jin J, Ni W, Qi W, Xuan Y*（通讯作者）. B7H4 is associated with stemness and cancer progression in esophageal squamous cell carcinoma. Hum Pathol. 2018, 80:152-162.
11.Yang Z, Ni W, Cui C, Qi W, Piao L, Xuan Y*（通讯作者）. Identification of LETM1 as a marker of cancer stem cells and predictor of poor prognosis in esophageal squamous cell carcinoma. Hum Pathol. 2018, 81:148-156.
12.Yang Z, Zhang C, Qi W, Cui C, Cui Y, Xuan Y*（通讯作者）. Tenascin-C as a prognostic determinant of colorectal cancer through induction of epithelial-to-mesenchymal transition and proliferation. Exp Mol Pathol. 2018,105(2):216-222.
13.Li-Li Lv, Zhao-Ting Yang, Tong-Hui Ma, Yan-Hua Xuan*（通讯作者）. Gli1, a potential cancer stem cell marker, is strongly associated with prognosis in prostate cancer. Int J Clin Exp Pathol. 2018,11(10): 4957-4966.
14.Yang Z, Zhang C, Qi W, Cui Y, Xuan Y*（通讯作者）. GLI1 promotes cancer stemness through intracellular signaling pathway PI3K/Akt/NFκB in colorectal adenocarcinoma. Exp Cell Res. 2018, 373(1-2):145-154.
15.Zhang C, Yuan Y, Fang L, Xuan Y*（通讯作者）. Promotion of osteogenesis by bioactive glass–ceramic coating through the Hedgehog signaling pathway. J Orthop Sci. 2019, 24(4),731-736.
16.Qi W, Yang Z, Li H, Cui Y, Xuan Y*（通讯作者）. The role of Tenascin-C and Twist1 in gastric cancer: cancer progression and prognosis. APMIS. 2019,127(2):64-71.
17.Yang Z, Zhang C, Feng Y, Qi W, Cui Y, Xuan Y*（通讯作者）. Tenascin-C is involved in promotion of cancer stemness via the Akt/HIF1ɑ axis in esophageal squamous cell carcinoma. Exp Mol Pathol. 2019,109,61-68.
18.Piao L, Feng Y, Yang Z, Qi W, Li H, Han H, Xuan Y*（通讯作者）. LETM1 is a potential cancer stem-like cell marker and predicts poor prognosis in colorectal adenocarcinoma. Pathol Res Pract. 2019,215(7).
19.Piao L, Yang Z, Feng Y, Zhang C, Cui C, Xuan Y*（通讯作者）. LETM1 is a potential biomarker of prognosis in lung non-small cell carcinoma. BMC Cancer. 2019,19(1):1-9.
20.Li H, Piao L, Xu D, Xuan Y*（通讯作者）. LETM1 is a potential biomarker that predicts poor prognosis in gastric adenocarcinoma. Exp Mol Pathol. 2020,112,1-11.
21.Piao L, Li H, Feng Y, Yang Z, Kim S, Xuan Y*（通讯作者）. SET domain-containing 5 is a potential prognostic biomarker that promotes esophageal squamous cell carcinoma stemness. Exp Cell Res. 2020, 389(1):111861.
22.Yang Z, Zhang C, Feng Y, Quan M, Cui Y, Xuan Y*（通讯作者）. Tenascin‑C predicts poor outcomes for patients with colorectal cancer and drives cancer stemness via Hedgehog signaling pathway. Cancer Cell Int. 2020,20:122.
23.Piao LH, Li HY, Feng Y, Li XG, Cui Y, Xuan YH*（通讯作者）. Leucine Zipper-EF-Hand Containing Transmembrane Protein 1 Is a Potential Prognostic Biomarker and Promotes Cell Progression in Prostate Cancer. Cancer Manag Res. 2020,12:1649-1660.
24.Qi WB,Yang ZT, Feng Y, Li HY, Che N, Liu L, Xuan YH*（通讯作者）. Gli1 Regulates Stemness Characteristics in Gastric Adenocarcinoma. Diagn Pathol. 2020,15(1):60.
25.Li H, Piao L, Liu S, Cui Y, Xuan Y*（通讯作者）. B7-H4 is a potential prognostic biomarker of prostate cancer. Exp Mol Pathol. 2020,114,104406.
26.Zhang CY, Yang ZT, Dong DL, Jang TS, Knowles JC, Kim HW, Jin GZ, Xuan YH*（通讯作者）. 3D culture technologies of cancer stem cells: promising ex vivo tumor models. J Tissue Eng. 2020, 24(11):2041731420933407.
27.Piao LH, Feng Y, Che N, Li MX, Li XG, Jin Y, Xuan YH*（通讯作者）. SETD8 is a prognostic biomarker that contributes to stem-like cell properties in non-small cell lung cancer. Pathol Res Pract. 2020, 216(12):153258.
28.Piao LH, Che N, Li HY, Li MX, Feng Y, Liu XZ, Kim SH, Jin Y, Xuan YH*（通讯作者）.SETD8 promotes stemness characteristics and is a potential prognostic biomarker of gastric adenocarcinoma. Exp Mol Pathol. 2020,117:104560.
29.Che N, Yang ZT, Liu XZ, Li MX, Feng Y, Zhang CY, Li C, Cui Y, Xuan YH*（通讯作者）. Suppression of LETM1 inhibits the proliferation and stemness of colorectal cancer cells through reactive oxygen species–induced autophagy. J Cell Mol Med. 2021,25(4):2110-2120.
30.Yang ZT, Zhang CY, Che N, Feng Y, Li C, Xuan YH*（通讯作者）. Su(var)3-9, Enhancer of Zeste, and Trithorax Domain-Containing 5 Facilitates Tumor Growth and Pulmonary Metastasis through Up-Regulation of AKT1 Signaling in Breast Cancer. Am J Pathol.. 2021,191(1):180-193.
31.Feng Y, Yang ZT, Zhang CY, Che N, Liu XZ, Xuan YH*（通讯作者）. B7-H4 induces epithelial-mesenchymal transition and promotes colorectal cancer stemness. Pathol Res Pract. 2021,218:15332.
32.Liu X, Li H, Che N, Zheng Y, Fan W, Li M, Li X, Xuan Y*（通讯作者）. HBXIP accelerates glycolysis and promotes cancer angiogenesis via AKT/mTOR pathway in bladder cancer. Exp Mol Pathol. 2021,121:104665.
33.Yang ZT#, Zhang CY#, Liu XZ#, Che N, Feng Y, Xuan YH*（通讯作者）.SETD5 Regulates Glycolysis in Breast Cancer Stem-Like Cells and Fuels Tumor Growth. Am J Pathol. 2022,19(1): S0002-9440(22)00006-2.
34.Qian Y, Liu X, Feng Y, Li X, Xuan Y*（通讯作者）. Tenascin C regulates cancer cell glycolysis and tumor progression in prostate cancer. Int J Urol. 2022,25.
35.Qian Y, Liu X, Feng Y, Li X, Xuan Y*（通讯作者）. Tenascin C regulates cancer cell glycolysis and tumor progression in prostate cancer. Int J Urol. 2022, 25.
36.Li M, Che N, Feng Y, Liu X, Piao L, Xuan Y*（通讯作者）, Jin Y. B7-H4 expression promotes non-small cell lung cancer progression via AMPK/mTOR signaling. Exp Mol Pathol. 2022, 9:104755.
二、科研课题：
1.阻断Hedgehog信号通路对宫颈癌侵袭和转移的作用；国家自然科学基金 (2010.01-2012.12) (No. 30960403), 24.0万元，主持
2.Hedgehog信号通路调控宫颈癌上皮间质转化的作用及机制；国家自然科学基金 (2012.01-2015.12) (No. 81160315), 46.0万元，主持
3.Hedgehog-Gli1信号通路调控Nanog参与宫颈癌干细胞自我更新中的作用及机制研究；国家自然科学基金 (2015.01-2018.12) (No. 81460390), 47.0万元，主持
4.Gli1对口腔种植体周围炎的作用及机制；吉林省教育厅“十三五”科学技术研究项目（2016.01-2017.12）（No.吉教科合字[2016]第266号），3万元，主持
5.NFκB介导的Gli1对食管癌干细胞特性的作用及机制研究；国家自然科学基金 (2018.01-2021.12) (No. 81760531), 34.0万元，主持
6.氧化铈/铂纳米颗粒介导肿瘤干性特征与M2型巨噬细胞极化调节食管癌顺铂耐药的作用机制；国家自然科学基金 (2022.01-2025.12) (No. 82160594), 34.1万元，主持
三、科研获奖：
1.玄延花,崔演,林贞花,孙凤丹,任香善. Hedgehog信号通路对宫颈癌的病理学意义. 吉林省科学技术奖三等奖, 2015年（2015Z30011)
2.杨昭婷，吕晓莹，尹永学，林贞花，李学敏，玄延花*，崔 演，金锡亨. Tenascin-C在食管鳞癌预后中的判定价值. 吉林省自然科学学术成果三等奖，2017年（20173113）
3.玄延花,崔演,杨昭婷，倪卫东，崔春爱，方龙云，金昱. Gli1调控的肿瘤微环境与干性特征对肿瘤预后的作用. 吉林省科学技术奖二等奖, 2020年（2020Z20018)
